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Aktuell tid och datum: tis mar 19 2024, 11:49
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Nya rön om hur ketamin får sin antidepressiva effekt
The experiments confirmed that the rapid antidepressant-like effects require activation of AMPA receptors, not inhibition of NMDA receptors.
Oväntat och mycket spännande, vidare:
This paper predicts that it would have a similar, very rapid onset of action and efficacy against treatment resistant depression to ketamine, but that it would lack some of the undesirable side effects such as percetual [sic] distortion and addiction potential
http://www.dailymail.co.uk/health/article-3573549/Secret-ketamine-eases-depression-unlocked-scientists-raising-hopes-new-faster-acting-antidepressants.html
#NMDA #AMPA #läkemedel #depression #ketamin
- i tor maj 05 2016, 11:55
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- Ämne: Nya rön om hur ketamin får sin antidepressiva effekt
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Ny studie visar på att ketamin kan ge varaktiga effekter mot depression
While controversial in academic settings, Dr. Henderson said his direct experience supports a different strategy for multiple-infusion treatment regimens and his clinical experience shows ketamine can invoke long-lasting effects often with less than six infusions.
"The wealth of clinical experience from treating hundreds of patients with ketamine has supplanted the preliminary data that emerged from the initial open-label and small double-blinded studies," said Dr. Henderson, who is a board certified psychiatrist, specializing in diagnosing and treating complex conditions, based in Denver, Colorado. He is also the co-founder of Neuro-Luminance Ketamine Infusion Centers.
Patients in the study completed the Quick Inventory of Depressive Symptoms (QIDS-SR), among other scales, and 80% showed persistent positive response to the ketamine infusions treatments.
http://www.prnewswire.com/news-releases/new-study-shows-ketamine-may-regenerate-brain-cells-relieving-depression-with-lasting-benefit-300237551.html
#artikel #läkemedel #ketamin #depression
- i fre mar 18 2016, 10:42
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- Ämne: Ny studie visar på att ketamin kan ge varaktiga effekter mot depression
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